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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MATK
All Species:
1.82
Human Site:
S490
Identified Species:
3.64
UniProt:
P42679
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42679
NP_002369.2
507
56469
S490
R
S
A
G
A
P
A
S
V
S
G
Q
D
A
D
Chimpanzee
Pan troglodytes
XP_512276
328
36052
V312
S
A
G
A
P
A
S
V
S
G
Q
D
A
D
G
Rhesus Macaque
Macaca mulatta
XP_001101430
450
50702
L434
A
A
M
R
P
S
F
L
Q
L
R
E
Q
L
E
Dog
Lupus familis
XP_854815
843
91685
T799
S
L
A
P
A
D
K
T
S
S
S
G
H
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P41242
505
56038
P488
R
S
V
G
V
S
A
P
A
G
G
Q
E
A
E
Rat
Rattus norvegicus
P41243
467
51878
A451
S
V
G
V
A
A
P
A
G
G
Q
E
A
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P41239
450
50733
H434
P
G
H
R
P
S
F
H
Q
L
R
E
Q
L
V
Frog
Xenopus laevis
P13116
532
59718
E516
E
Y
L
Q
A
F
L
E
D
Y
F
T
A
T
E
Zebra Danio
Brachydanio rerio
XP_695792
445
50295
S429
T
E
P
K
K
R
P
S
F
H
K
L
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731611
1052
113728
R1034
W
D
L
N
P
A
K
R
P
T
F
A
E
L
K
Honey Bee
Apis mellifera
XP_393399
493
55500
I477
K
R
P
T
F
Y
D
I
K
L
V
L
G
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795344
763
85563
R747
W
D
I
N
P
K
K
R
P
T
F
K
H
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.6
47.1
56.8
N.A.
87.1
82.2
N.A.
N.A.
46.9
34
56
N.A.
24.8
40
N.A.
32.2
Protein Similarity:
100
64.6
64.6
58.8
N.A.
92.3
87.5
N.A.
N.A.
65.6
49.2
71.4
N.A.
33.1
57.5
N.A.
42.9
P-Site Identity:
100
0
0
20
N.A.
46.6
6.6
N.A.
N.A.
0
6.6
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
13.3
20
33.3
N.A.
60
20
N.A.
N.A.
6.6
13.3
6.6
N.A.
13.3
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
17
9
34
25
17
9
9
0
0
9
25
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
9
9
0
9
0
0
9
9
9
9
% D
% Glu:
9
9
0
0
0
0
0
9
0
0
0
25
17
17
25
% E
% Phe:
0
0
0
0
9
9
17
0
9
0
25
0
0
0
0
% F
% Gly:
0
9
17
17
0
0
0
0
9
25
17
9
9
0
17
% G
% His:
0
0
9
0
0
0
0
9
0
9
0
0
17
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
9
9
25
0
9
0
9
9
0
0
9
% K
% Leu:
0
9
17
0
0
0
9
9
0
25
0
17
0
25
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
17
9
42
9
17
9
17
0
0
0
0
0
9
% P
% Gln:
0
0
0
9
0
0
0
0
17
0
17
17
17
9
0
% Q
% Arg:
17
9
0
17
0
9
0
17
0
0
17
0
9
0
17
% R
% Ser:
25
17
0
0
0
25
9
17
17
17
9
0
0
9
0
% S
% Thr:
9
0
0
9
0
0
0
9
0
17
0
9
0
9
0
% T
% Val:
0
9
9
9
9
0
0
9
9
0
9
0
0
9
9
% V
% Trp:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _